Searchable abstracts of presentations at key conferences in endocrinology

ea0092op-01-04 | Oral Session 1: Highlights in Thyroidology: in Memory of Jacques Dumont | ETA2023

Should hypothyroxinaemia during early gestation be regarded as a condition of oxidative stress?

Pop Victor , Krabbe Hans , Broeren Maarten , Wiersinga Wilmar , Rayman Margaret

Background: Normal pregnancy is a state of physiological oxidative stress (OS) with oxidants facilitating the implantation of the embryo and optimal decidualisation but counterbalanced by antioxidants. Pro-oxidant processes exceeding the anti-oxidants capacity result in imbalanced OS, which has been associated with the ‘’big four’’ obstetric complications: pre-term birth, intra-uterine growth retardation, pre-eclampsia and diabetes gravidarum. Important OS ...